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Adenine monohydrochloride hemihydrate

🥰Excellent
Catalog No. T5081Cas No. 6055-72-7
Alias Adenine hydrochloride hydrate, 6-Aminopurine hydrochloride hydrate

Adenine monohydrochloride hemihydrate is a high affinity adenine receptor agonist (Ki = 18 nM at rat adenine receptor). It inhibits forskolin-stimulated cAMP formation in CHO cells transfected with the adenine receptor and also stimulates GTPγS binding (pEC50 values are 8.54 and 7.21 respectively).

Adenine monohydrochloride hemihydrate

Adenine monohydrochloride hemihydrate

🥰Excellent
Purity: 97.61%
Catalog No. T5081Alias Adenine hydrochloride hydrate, 6-Aminopurine hydrochloride hydrateCas No. 6055-72-7
Adenine monohydrochloride hemihydrate is a high affinity adenine receptor agonist (Ki = 18 nM at rat adenine receptor). It inhibits forskolin-stimulated cAMP formation in CHO cells transfected with the adenine receptor and also stimulates GTPγS binding (pEC50 values are 8.54 and 7.21 respectively).
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1 g$29In Stock
1 mL x 10 mM (in DMSO)$39In Stock
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Purity:97.61%
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Product Introduction

Bioactivity
Description
Adenine monohydrochloride hemihydrate is a high affinity adenine receptor agonist (Ki = 18 nM at rat adenine receptor). It inhibits forskolin-stimulated cAMP formation in CHO cells transfected with the adenine receptor and also stimulates GTPγS binding (pEC50 values are 8.54 and 7.21 respectively).
Targets&IC50
Adenosine receptor:18 nM (Ki)
In vivo
Procyclidine is used as antiparkinsonian agents because of their anti-cholinergic action is also known to have NMDA antagonist properties. Unlike other NMDA antagonists, this agents-because of their anti-cholinergic action-are devoid of neurotoxic side effects [1].
AliasAdenine hydrochloride hydrate, 6-Aminopurine hydrochloride hydrate
Chemical Properties
Molecular Weight189.6
FormulaC5H8ClN5O
Cas No.6055-72-7
SmilesO.Cl.Nc1ncnc2nc[nH]c12
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (263.71 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM5.2743 mL26.3713 mL52.7426 mL263.7131 mL
5 mM1.0549 mL5.2743 mL10.5485 mL52.7426 mL
10 mM0.5274 mL2.6371 mL5.2743 mL26.3713 mL
20 mM0.2637 mL1.3186 mL2.6371 mL13.1857 mL
50 mM0.1055 mL0.5274 mL1.0549 mL5.2743 mL
100 mM0.0527 mL0.2637 mL0.5274 mL2.6371 mL

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