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Adenine monohydrochloride hemihydrate
Catalog No. T5081Cas No. 6055-72-7
Alias Adenine hydrochloride hydrate, 6-Aminopurine hydrochloride hydrate
Adenine monohydrochloride hemihydrate is a high affinity adenine receptor agonist (Ki = 18 nM at rat adenine receptor). It inhibits forskolin-stimulated cAMP formation in CHO cells transfected with the adenine receptor and also stimulates GTPγS binding (pEC50 values are 8.54 and 7.21 respectively).
Adenine monohydrochloride hemihydrate
Catalog No. T5081Alias Adenine hydrochloride hydrate, 6-Aminopurine hydrochloride hydrateCas No. 6055-72-7
Adenine monohydrochloride hemihydrate is a high affinity adenine receptor agonist (Ki = 18 nM at rat adenine receptor). It inhibits forskolin-stimulated cAMP formation in CHO cells transfected with the adenine receptor and also stimulates GTPγS binding (pEC50 values are 8.54 and 7.21 respectively).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 g | $29 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $39 | In Stock |
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Purity:97.61%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Adenine monohydrochloride hemihydrate is a high affinity adenine receptor agonist (Ki = 18 nM at rat adenine receptor). It inhibits forskolin-stimulated cAMP formation in CHO cells transfected with the adenine receptor and also stimulates GTPγS binding (pEC50 values are 8.54 and 7.21 respectively). |
| Targets&IC50 | Adenosine receptor:18 nM (Ki) |
| In vivo | Procyclidine is used as antiparkinsonian agents because of their anti-cholinergic action is also known to have NMDA antagonist properties. Unlike other NMDA antagonists, this agents-because of their anti-cholinergic action-are devoid of neurotoxic side effects [1]. |
| Alias | Adenine hydrochloride hydrate, 6-Aminopurine hydrochloride hydrate |
| Molecular Weight | 189.6 |
| Formula | C5H8ClN5O |
| Cas No. | 6055-72-7 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (263.71 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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