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Adenine monohydrochloride hemihydrate is a high affinity adenine receptor agonist (Ki = 18 nM at rat adenine receptor). It inhibits forskolin-stimulated cAMP formation in CHO cells transfected with the adenine receptor and also stimulates GTPγS binding (pEC50 values are 8.54 and 7.21 respectively).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 g | $29 | In Stock | |
1 mL x 10 mM (in DMSO) | $39 | In Stock |
Description | Adenine monohydrochloride hemihydrate is a high affinity adenine receptor agonist (Ki = 18 nM at rat adenine receptor). It inhibits forskolin-stimulated cAMP formation in CHO cells transfected with the adenine receptor and also stimulates GTPγS binding (pEC50 values are 8.54 and 7.21 respectively). |
Targets&IC50 | Adenosine receptor:18 nM (Ki) |
In vivo | Procyclidine is used as antiparkinsonian agents because of their anti-cholinergic action is also known to have NMDA antagonist properties. Unlike other NMDA antagonists, this agents-because of their anti-cholinergic action-are devoid of neurotoxic side effects [1]. |
Alias | Adenine hydrochloride hydrate, 6-Aminopurine hydrochloride hydrate |
Molecular Weight | 189.6 |
Formula | C5H8ClN5O |
Cas No. | 6055-72-7 |
Smiles | O.Cl.Nc1ncnc2nc[nH]c12 |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 50 mg/mL (263.71 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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