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Ampreloxetine
Catalog No. T26622Cas No. 1227056-84-9
Alias TD-9855, TD9855, TD 9855
Ampreloxetine (TD-9855), a norepinephrine reuptake inhibitor, is used to study neurological diseases.
Ampreloxetine
Catalog No. T26622Alias TD-9855, TD9855, TD 9855Cas No. 1227056-84-9
Ampreloxetine (TD-9855), a norepinephrine reuptake inhibitor, is used to study neurological diseases.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | $1,520 | 6-8 weeks |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Ampreloxetine (TD-9855), a norepinephrine reuptake inhibitor, is used to study neurological diseases. |
| In vivo | Ampreloxetine (TD-9855) is a novel, investigational, selective NET inhibitor. Its > 24-h half-life allows once-daily dosing. Persistent elevation of plasma NE levels accompanied by reduced DHPG levels after ampreloxetine suggests reduced neuronal reuptake and metabolism of NE in postganglionic efferent sympathetic neurons (5-day escalating doses, followed by 20 weeks of open-label treatment and a 4-week withdrawal).[1] |
| Alias | TD-9855, TD9855, TD 9855 |
| Molecular Weight | 321.34 |
| Formula | C18H18F3NO |
| Cas No. | 1227056-84-9 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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