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anemarsaponin B

Catalog No. T7030 CAS 139051-27-7

Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activity, possibly via the p38 MAP kinase pathway. Anemarsaponin B can inhibit PAF-induced rabbit platelet aggregation in vitro.

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anemarsaponin B, CAS 139051-27-7

Pack Size	Availability	Price/USD
1 mg	In stock	$ 84.00
5 mg	In stock	$ 196.00
10 mg	In stock	$ 295.00
25 mg	In stock	$ 497.00
50 mg	In stock	$ 723.00
1 mL * 10 mM (in DMSO)	In stock	$ 327.00

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Purity: 99.81%

Purity: 99.06%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activity, possibly via the p38 MAP kinase pathway. Anemarsaponin B can inhibit PAF-induced rabbit platelet aggregation in vitro.
Source	Natural Products > Liliaceae > Anemarrhena

Molecular Weight	903.06
Formula	C45H74O18
CAS No.	139051-27-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 27.5 mg/mL (30.45 mM)

References and Literature

1. Kim J Y, et al. Anti-inflammatory effect of anemarsaponin B isolated from the rhizomes of Anemarrhena asphodeloides in LPS-induced RAW 264.7 macrophages is mediated by negative regulation of the nuclear factor-kappaB and p38 pathways.[J]. Food & Chemical Toxicology, 2009, 47(7):1610-1617. 2. Dong J X, Han G Y. A new active steroidal saponin from Anemarrhena asphodeloides[J]. Planta Medica, 1991, 57(05):460-462.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Kinase Inhibitor Library Anti-Tumor Natural Product Library Natural Product Library for HTS Anti-Aging Compound Library Anti-Pancreatic Cancer Compound Library Anti-Colorectal Cancer Traditional Chinese Medicine Compound Library Human Metabolite Library Anti-Obesity Compound Library Selected Plant-Sourced Compound Library

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Keywords

anemarsaponin B 139051-27-7 Immunology/Inflammation MAPK Neuroscience NF-Κb p38 MAPK NF-κB NO Synthase COX MEK Nuclear factor-kappaB MAP2K Mitogen-activated protein kinase kinase MAPKK Nuclear factor-κB NOS Cyclooxygenase Inhibitor Nitric oxide synthases inhibit inhibitor

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