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Anticancer agent 110
🥰Excellent
Catalog No. T78904Cas No. 887349-03-3
Anticancer agent 110 is an anticancer compound with cytotoxic, antitumor, and antileukemic activity that triggers DNA damage and apoptosis and is used in the study of chronic granulocytic leukemia.
Anticancer agent 110
🥰Excellent
Catalog No. T78904Cas No. 887349-03-3
Anticancer agent 110 is an anticancer compound with cytotoxic, antitumor, and antileukemic activity that triggers DNA damage and apoptosis and is used in the study of chronic granulocytic leukemia.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | $1,520 | In Stock | |
| 50 mg | $1,980 | In Stock | |
| 100 mg | $2,500 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Anticancer agent 110 is an anticancer compound with cytotoxic, antitumor, and antileukemic activity that triggers DNA damage and apoptosis and is used in the study of chronic granulocytic leukemia. |
| Targets&IC50 | K562 cells:0.7 μM |
| In vitro | Anticancer agent 110 exhibited an inhibitory effect on leukemic K-562 cells at concentrations ranging from 0.01 μM to 100 μM, with an IC50 value of 0.7 μM. The compound triggered higher levels of DNA damage in K-562 cells after 24 hours of treatment at concentrations of 70 nM and 700 nM, and also caused cellular morphological changes, exhibiting apoptotic features. [1] |
| Molecular Weight | 380.4 |
| Formula | C18H13FN6OS |
| Cas No. | 887349-03-3 |
| Smiles | O=C(NC1=NC=C(S1)CC2=CC=C(F)C=C2)C3=CC=C(C=C3)N4N=NN=C4 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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