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ASP7663
Catalog No. T8410Cas No. 1190217-35-6
ASP7663 is a TRPA1 Receptor Agonist and exhibiting an abdominal analgesic effect in vivo.
ASP7663
Catalog No. T8410Cas No. 1190217-35-6
ASP7663 is a TRPA1 Receptor Agonist and exhibiting an abdominal analgesic effect in vivo.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $33 | In Stock | |
| 5 mg | $75 | In Stock | |
| 10 mg | $113 | In Stock | |
| 25 mg | $229 | In Stock | |
| 50 mg | $348 | In Stock | |
| 100 mg | $523 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $83 | In Stock |
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CitedSelect Batch
Purity:98.11%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | ASP7663 is a TRPA1 Receptor Agonist and exhibiting an abdominal analgesic effect in vivo. |
| In vivo | ASP7663, a novel and selective TRPA1 agonist, in constipation models as well as an abdominal pain model.?ASP7663 activated human, rat, and mouse TRPA1 and released 5-HT from QGP-1 cells, and oral but not intravenous administration of ASP7663 significantly improved the loperamide-induced delay in colonic transit in mice.?While pretreatment with the TRPA1 antagonist HC-030031 and vagotomy both inhibited the ameliorating effect of oral ASP7663 on the colonic transit, both orally and intravenously administered ASP7663 significantly inhibited colorectal distension (CRD)-induced abdominal pain response in rats[1]. |
| Molecular Weight | 263.26 |
| Formula | C14H14FNO3 |
| Cas No. | 1190217-35-6 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 11 mg/mL (41.78 mM)  | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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