Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Bcl-xL antagonist 2 is an effective and selective antagonist of Bcl-xL with an IC50 of 91 nM and a Ki of 65 nM. Bcl-xL antagonist 2 induces apoptosis in cancer cells and can be used in studies about chronic lymphocytic leukemia and non-Hodgkin’s lymphoma.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 147.00 | |
5 mg | In stock | $ 372.00 | |
10 mg | In stock | $ 556.00 | |
25 mg | In stock | $ 896.00 | |
50 mg | In stock | $ 1,220.00 | |
100 mg | In stock | $ 1,650.00 | |
500 mg | In stock | $ 3,290.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 397.00 |
Description | Bcl-xL antagonist 2 is an effective and selective antagonist of Bcl-xL with an IC50 of 91 nM and a Ki of 65 nM. Bcl-xL antagonist 2 induces apoptosis in cancer cells and can be used in studies about chronic lymphocytic leukemia and non-Hodgkin’s lymphoma. |
Targets&IC50 | BCL-XL:0.091 μM |
In vivo | Bcl-xL antagonist 2 (1 mg/kg;i.v.) exhibits good PK profile with CL, Vss, t1/2 and F of 0.47 mL/min/kg, 0.16 L/kg, 6.0 h and 16% in rats[1]. |
Molecular Weight | 436.51 |
Formula | C21H16N4O3S2 |
CAS No. | 1235032-75-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (114.5 mM), Sonification is recommended.
You can also refer to dose conversion for different animals. More
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Bcl-xL antagonist 2 1235032-75-3 Apoptosis BCL Bcl xL antagonist 2 BclxL antagonist 2 inhibitor inhibit