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BDP9066
🥰Excellent
Catalog No. T14521Cas No. 2226507-04-4
BDP9066 is a potent and selective MRCK inhibitor that inhibits MRCKβ and MRCKα/β and can be used for the prevention and treatment of skin cancer.
BDP9066
🥰Excellent
Purity: 98.18%
Catalog No. T14521Cas No. 2226507-04-4
BDP9066 is a potent and selective MRCK inhibitor that inhibits MRCKβ and MRCKα/β and can be used for the prevention and treatment of skin cancer.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $52 | In Stock | |
| 5 mg | $123 | In Stock | |
| 10 mg | $198 | In Stock | |
| 25 mg | $455 | In Stock | |
| 50 mg | $787 | In Stock | |
| 100 mg | $1,360 | In Stock | |
| 500 mg | $2,720 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $135 | In Stock |
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Purity:98.18%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | BDP9066 is a potent and selective MRCK inhibitor that inhibits MRCKβ and MRCKα/β and can be used for the prevention and treatment of skin cancer. |
| Targets&IC50 | MRCKα/β:0.0136 nM/0.0233 nM ( Ki), MRCKβ (SCC12 cells):64 nM, MRCKα/β:（ki）0.0136 nM/0.0233 nM |
| In vitro | Among over 750 human cancer cell lines tested, BDP9066 consistently exhibited anti-proliferative activity in hematologic cancer cells[1]. |
| In vivo | As an effective and selective MRCK inhibitor, BDP9066, in a two-stage chemical carcinogenesis model of mouse squamous cell carcinoma, reduced MRCKα S1003 phosphorylation and the growth of skin tumors with local treatment. |
| Molecular Weight | 348.44 |
| Formula | C20H24N6 |
| Cas No. | 2226507-04-4 |
| Smiles | C1CC[C@@]2(CCCN(C2)c2cc[nH]c3ncc(-c4ccncn4)c23)NC1 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 8 mg/mL (22.96 mM), Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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