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Canrenone

Catalog No. T0354Cas No. 976-71-6
Alias SC9376, SC14266, RP-11614, Aldadiene, 6,7-Dehydro-7α-desthioacetylspironolactone

Canrenone (SC14266) is an aldosterone antagonist with potassium-sparing diuretic activity.

Canrenone

Canrenone

Purity: 99.8%
Catalog No. T0354Alias SC9376, SC14266, RP-11614, Aldadiene, 6,7-Dehydro-7α-desthioacetylspironolactoneCas No. 976-71-6
Canrenone (SC14266) is an aldosterone antagonist with potassium-sparing diuretic activity.
Pack SizePriceAvailabilityQuantity
25 mg$30In Stock
50 mg$39In Stock
1 mL x 10 mM (in DMSO)$43In Stock
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Purity:99.8%
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Product Introduction

Bioactivity
Description
Canrenone (SC14266) is an aldosterone antagonist with potassium-sparing diuretic activity.
AliasSC9376, SC14266, RP-11614, Aldadiene, 6,7-Dehydro-7α-desthioacetylspironolactone
Chemical Properties
Molecular Weight340.46
FormulaC22H28O3
Cas No.976-71-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 34.1 mg/mL (100 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9372 mL14.6860 mL29.3720 mL146.8601 mL
5 mM0.5874 mL2.9372 mL5.8744 mL29.3720 mL
10 mM0.2937 mL1.4686 mL2.9372 mL14.6860 mL
20 mM0.1469 mL0.7343 mL1.4686 mL7.3430 mL
50 mM0.0587 mL0.2937 mL0.5874 mL2.9372 mL
100 mM0.0294 mL0.1469 mL0.2937 mL1.4686 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Dose Conversion

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