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Ceftriaxone sodium hydrate

Ceftriaxone sodium hydrate
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Purity:99.64%
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Ceftriaxone sodium hydrate

Catalog No. T1223Cas No. 104376-79-6
Ceftriaxone sodium hydrate is a broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears.
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Pack SizePriceAvailabilityQuantity
50 mg$30In Stock
100 mg$41In Stock
200 mg$59In Stock
500 mg$97In Stock
1 mL x 10 mM (in DMSO)$39In Stock
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Product Introduction

Bioactivity
Description
Ceftriaxone sodium hydrate is a broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears.
In vivo
Ceftriaxone maintains stability against β-lactamase enzymes produced by many bacteria, yet the β-lactamases from B. fragilis, some Klebsiella species, P. vulgaris, and P. aeruginosa can deactivate it. Ceftriaxone sodium trihydrate exhibits broad-spectrum in vitro activity against both Gram-positive and Gram-negative bacteria, aerobes, and certain anaerobes. It is effective against Staphylococcus aureus strains, whether penicillin-sensitive or penicillin-resistant (MIC90, 2 to 8 mg/L). However, its efficacy is compromised against strains resistant to methicillin or oxacillin.
AliasCeftriaxone Sodium Trihydrate, Ceftriaxone disodium hemiheptahydrate, Ceftriaxone sodium
Chemical Properties
Molecular Weight661.6
FormulaC18H16N8Na2O7S3·3.5H2O
Cas No.104376-79-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 60 mg/mL (90.69 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.5115 mL7.5574 mL15.1149 mL75.5744 mL
5 mM0.3023 mL1.5115 mL3.0230 mL15.1149 mL
10 mM0.1511 mL0.7557 mL1.5115 mL7.5574 mL
20 mM0.0756 mL0.3779 mL0.7557 mL3.7787 mL
50 mM0.0302 mL0.1511 mL0.3023 mL1.5115 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
1 Enter information below:
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