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Ceftriaxone sodium hydrate is a broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 mg | $30 | In Stock | |
100 mg | $41 | In Stock | |
200 mg | $59 | In Stock | |
500 mg | $97 | In Stock | |
1 mL x 10 mM (in DMSO) | $39 | In Stock |
Description | Ceftriaxone sodium hydrate is a broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears. |
In vivo | Ceftriaxone maintains stability against β-lactamase enzymes produced by many bacteria, yet the β-lactamases from B. fragilis, some Klebsiella species, P. vulgaris, and P. aeruginosa can deactivate it. Ceftriaxone sodium trihydrate exhibits broad-spectrum in vitro activity against both Gram-positive and Gram-negative bacteria, aerobes, and certain anaerobes. It is effective against Staphylococcus aureus strains, whether penicillin-sensitive or penicillin-resistant (MIC90, 2 to 8 mg/L). However, its efficacy is compromised against strains resistant to methicillin or oxacillin. |
Alias | Ceftriaxone Sodium Trihydrate, Ceftriaxone disodium hemiheptahydrate |
Molecular Weight | 661.6 |
Formula | C18H16N8Na2O7S3·3.5H2O |
Cas No. | 104376-79-6 |
Smiles | [Na+].[Na+].[Na+].[Na+].O.O.O.O.O.O.O.Nc1scc(n1)\C(=N\OC)C(=O)N[C@@H]3C(=O)N4C(C([O-])=O)=C(CSC2=NC(=O)C([O-])=NN2C)CS[C@H]34.Nc1scc(n1)\C(=N\OC)C(=O)N[C@@H]3C(=O)N4C(=C(CSC2=NC(=O)C([O-])=NN2C)CS[C@H]34)C([O-])=O |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 60 mg/mL (90.69 mM) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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