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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $51 | In Stock | |
5 mg | $122 | In Stock | |
10 mg | $198 | In Stock | |
25 mg | $372 | In Stock | |
50 mg | $556 | In Stock | |
100 mg | $783 | In Stock | |
1 mL x 10 mM (in DMSO) | $153 | In Stock |
Description | CH7057288 is an effective and selective TRK inhibitor with an IC50 value of 1.1 nM, 7.8 nM and 5.1 nM for TRKA, TRKB and TRKC, respectively. |
Targets&IC50 | TrkC:5.1 nM, TrkB:7.8 nM , TrkA:1.1 nM |
In vitro | CH7057288, a potent and selective TRK inhibitor belonging to a novel chemical class.CH7057288 induced regression of intracranial tumors and greatly improved event-free survival in an intracranial implantation model mimicking brain metastasis. |
Molecular Weight | 569.67 |
Formula | C32H31N3O5S |
Cas No. | 2095616-82-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 34 mg/mL (59.68 mM) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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