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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $42 | In Stock | |
5 mg | $98 | In Stock | |
10 mg | $163 | In Stock | |
25 mg | $317 | In Stock | |
50 mg | $468 | In Stock | |
100 mg | $689 | In Stock |
Description | CHDI-390576 is a CNS-permeable, selective and potent dibenzoyl isohydroxamic acid class IIa histone deacetylase (HDAC) inhibitor that inhibits class IIa HDAC 4, HDAC 5, HDAC 7, HDAC 9, and can be used in cancer research. |
Targets&IC50 | HDAC5:60 nM, HDAC3:25.8 μM, HDAC7:31 nM, HDAC1:39.7 μM, HDAC4:54 nM, HDAC8:9.1 μM, HDAC9 (human):50 nM, HDAC6 (human):6.2 μM |
In vitro | CHDI-390576 exhibits good affinity to the catalytic domain of HDAC4, and it inhibits class I HDACs (1, 3, 8) and class IIb HDAC6[1]. |
Molecular Weight | 391.32 |
Formula | C19H13F4N3O2 |
Cas No. | 1629729-98-1 |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 200 mg/mL (511.09 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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