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Cletoquine hydrochloride

Cletoquine hydrochloride
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Purity:98.4%
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Cletoquine hydrochloride

Catalog No. T10835L1Cas No. 159358-29-9
Cletoquine hydrochloride is a major active metabolite of Hydroxychloroquine. Cletoquine hydrochloride is a Chloroquine derivative and exhibits the ability to against the chikungunya virus (CHIKV). Cletoquine hydrochloride exhibits antimalarial effects.
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Pack SizePriceAvailabilityQuantity
1 mg$197In Stock
5 mg$478In Stock
10 mg$654In Stock
25 mg$990In Stock
50 mg$1,330In Stock
100 mg$1,750In Stock
1 mL x 10 mM (in DMSO)$551In Stock
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Product Introduction

Bioactivity
Description
Cletoquine hydrochloride is a major active metabolite of Hydroxychloroquine. Cletoquine hydrochloride is a Chloroquine derivative and exhibits the ability to against the chikungunya virus (CHIKV). Cletoquine hydrochloride exhibits antimalarial effects.
In vivo
Hydroxychloroquine (5 mg/kg; intravenously) is administered to BALB/c mice for blood and tissue to determine the content of Cletoquine. The tissue to blood concentration ratio (Kp) is ≥1, indicating accumulation of Cletoquine in tissues. The Cletoquine Kp ratio for the various tissues are observed of liver (114.3)>kidney (24.4)>spleen (19.3)>lungs (16.5)>heart (5.5)[3].
AliasCletoquine hydrochloride( 4298-15-1 Free base)
Chemical Properties
Molecular Weight344.28
FormulaC16H23Cl2N3O
Cas No.159358-29-9
Storage & Solubility Information
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 4 mg/mL (11.62 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9046 mL14.5231 mL29.0461 mL145.2306 mL
5 mM0.5809 mL2.9046 mL5.8092 mL29.0461 mL
10 mM0.2905 mL1.4523 mL2.9046 mL14.5231 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
1 Enter information below:
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