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Corin is an irreversible inhibitor of HDAC1(IC50 = 147 nM) and LSD1(Ki = 110 nM).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $179 | In Stock | |
5 mg | $455 | In Stock | |
10 mg | $672 | In Stock | |
25 mg | $1,060 | In Stock | |
50 mg | $1,430 | In Stock | |
100 mg | $1,920 | In Stock | |
1 mL x 10 mM (in DMSO) | $490 | In Stock |
Description | Corin is an irreversible inhibitor of HDAC1(IC50 = 147 nM) and LSD1(Ki = 110 nM). |
Targets&IC50 | HDAC1:147 nM , LSD1:110 nM |
In vitro | Corin induces cellular H3K9 acetylation(EC50 = 95 nM) and is non-toxic to primary human melanocytes[1]. |
Molecular Weight | 428.53 |
Formula | C26H28N4O2 |
Cas No. | 1808113-09-8 |
Smiles | N[C@@H]1C[C@H]1c1ccc(NC(=O)CCCc2ccc(cc2)C(=O)Nc2ccccc2N)cc1 |
Relative Density. | 1.287 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | H2O: Insoluble DMSO: 90.0 mg/mL (210.0 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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