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Cucurbitacin IIb

Cucurbitacin IIb
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Purity:100%
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Cucurbitacin IIb

Catalog No. T4S1469Cas No. 50298-90-3
1. Cucurbitacin IIb is one of the major active compounds in Hemsleyadine tablets which have been used for clinical treatment of bacillary dysentery, enteritis and acute tonsilitis. 2. Cucurbitacin IIb exhibits its anti-inflammatory activity through modulating multiple cellular behaviors and signaling pathways, leading to the suppression of the adaptive immune response.
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Pack SizePriceAvailabilityQuantity
1 mg$97In Stock
5 mg$219In Stock
10 mg$378In Stock
25 mg$623In Stock
50 mg$882In Stock
100 mg$1,180In Stock
1 mL x 10 mM (in DMSO)$253In Stock
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Product Introduction

Bioactivity
Description
1. Cucurbitacin IIb is one of the major active compounds in Hemsleyadine tablets which have been used for clinical treatment of bacillary dysentery, enteritis and acute tonsilitis. 2. Cucurbitacin IIb exhibits its anti-inflammatory activity through modula
Chemical Properties
Molecular Weight520.7
FormulaC30H48O7
Cas No.50298-90-3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 65 mg/mL (124.83 mM)
Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.9205 mL9.6025 mL19.2049 mL96.0246 mL
5 mM0.3841 mL1.9205 mL3.8410 mL19.2049 mL
10 mM0.1920 mL0.9602 mL1.9205 mL9.6025 mL
20 mM0.0960 mL0.4801 mL0.9602 mL4.8012 mL
50 mM0.0384 mL0.1920 mL0.3841 mL1.9205 mL
100 mM0.0192 mL0.0960 mL0.1920 mL0.9602 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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