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Diatrizoic Acid

Catalog No. T1395Cas No. 117-96-4
Alias Diatrizoate, Amidotrizoic acid

Diatrizoic Acid (Amidotrizoic acid) is an organic, iodinated radiopaque X-ray contrast medium used in diagnostic radiography.

Diatrizoic Acid

Diatrizoic Acid

Purity: 100%
Catalog No. T1395Alias Diatrizoate, Amidotrizoic acidCas No. 117-96-4
Diatrizoic Acid (Amidotrizoic acid) is an organic, iodinated radiopaque X-ray contrast medium used in diagnostic radiography.
Pack SizePriceAvailabilityQuantity
1 g$34In Stock
5 g$77In Stock
10 g$113In Stock
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Purity:100%
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Product Introduction

Bioactivity
Description
Diatrizoic Acid (Amidotrizoic acid) is an organic, iodinated radiopaque X-ray contrast medium used in diagnostic radiography.
Kinase Assay
Radiochemical enzyme assays for COX-1 and COX-2: 10 μL of purified COX-1 (0.7-0.8 μg) or COX-2 (3.0 units, 0.3μg) is activated with 50 μL of cofactor solution [l-epinephrine (1.3 mg/mL), reduced glutathione (0.3 mg/mL), and hematin (1.3 mg/mL) in oxygen-free Tris-HCl buffer (pH 8.0)]. The enzyme solution (60 μL) is added to Ibuprofen solutions or DMSO (20 μL) after [14C]arachidonic acid is added in 0.2 mL eight-strip test tubes and preincubated 10 minutes on ice. Samples are incubated for 15 minutes at 37 °C, after which the reaction is terminated by addition of 10 μL of 2 M HCl and 5 μL of carrier solution (PGE2 and PGF2α, 0.2 μg/mL of each in EtOH). The unmetabolized arachidonic acid is separated from the prostaglandin products by column chromatography and eluted with n-hexane-dioxane-glacial acetic acid (70:30:1). The prostaglandin products are then eluted with EtOAc-MeOH (85:15), and the samples are counted in a Packard scintillation spectrometer. IC50 values are obtained by linear regression analysis.
AliasDiatrizoate, Amidotrizoic acid
Chemical Properties
Molecular Weight613.91
FormulaC11H9I3N2O4
Cas No.117-96-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/mL (89.59 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.6289 mL8.1445 mL16.2890 mL81.4452 mL
5 mM0.3258 mL1.6289 mL3.2578 mL16.2890 mL
10 mM0.1629 mL0.8145 mL1.6289 mL8.1445 mL
20 mM0.0814 mL0.4072 mL0.8145 mL4.0723 mL
50 mM0.0326 mL0.1629 mL0.3258 mL1.6289 mL

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