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Dimethyl lithospermate B

Catalog No. T8299Cas No. 875313-64-7
Alias dmLSB

Dimethyl lithospermate B (dmLSB) is a selective Na+ channel agonist.

Dimethyl lithospermate B

Dimethyl lithospermate B

Purity: 99.62%
Catalog No. T8299Alias dmLSBCas No. 875313-64-7
Dimethyl lithospermate B (dmLSB) is a selective Na+ channel agonist.
Pack SizePriceAvailabilityQuantity
1 mg$179In Stock
5 mg$479In Stock
10 mg$687In Stock
25 mg$1,050In Stock
50 mg$1,390In Stock
100 mg$1,890In Stock
1 mL x 10 mM (in DMSO)$579In Stock
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Purity:99.62%
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Product Introduction

Bioactivity
Description
Dimethyl lithospermate B (dmLSB) is a selective Na+ channel agonist.
In vitro
Dimethyl lithospermate B slows inactivation of sodium current (INa), leading to the increased inward current during the early phases of the action potential [1][2].
AliasdmLSB
Chemical Properties
Molecular Weight746.67
FormulaC38H34O16
Cas No.875313-64-7
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 22.5 mg/mL (30.13 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.3393 mL6.6964 mL13.3928 mL66.9640 mL
5 mM0.2679 mL1.3393 mL2.6786 mL13.3928 mL
10 mM0.1339 mL0.6696 mL1.3393 mL6.6964 mL
20 mM0.0670 mL0.3348 mL0.6696 mL3.3482 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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