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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $49 | In Stock | |
5 mg | $118 | In Stock | |
10 mg | $178 | In Stock | |
25 mg | $297 | In Stock | |
50 mg | $441 | In Stock | |
100 mg | $592 | In Stock | |
500 mg | Inquiry | In Stock | |
1 mL x 10 mM (in DMSO) | $135 | In Stock |
Description | Droloxifene (3-Hydroxytamoxifen), a tamoxifen derivative, is an oral active and selective estrogen receptor modulator.Droloxifene induced p53 expression and apoptosis in McF-7 cells.Fluroxifene has anti-estrogen and anti-implantation effects.Fluroxifene prevented bone loss in ovariectomized rats. |
In vitro | Droloxifene induces apoptosis in MCF-7 cells(10 nM; 16-18 hours)[1]. |
In vivo | Droloxifene (5-20 mg/kg,P.o.;Daily for 4 weeks can bring THE BMD of DFM up to 10mg/kg and completely prevent OVX from reducing the BMC and BMD of DFM at 20mg /kg/day[1]. |
Alias | 3-Hydroxytamoxifen |
Molecular Weight | 387.51 |
Formula | C26H29NO2 |
Cas No. | 82413-20-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 40 mg/mL (103.22 mM), Sonication is recommended. ![]() | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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