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Esmolol hydrochloride

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Catalog No. T1503Cas No. 81161-17-3
Alias Esmolol HCl, ASL8052

Esmolol is a cardioselective beta-blocker used in parenteral forms in the treatment of arrhythmias and severe hypertension. Esmolol has not been linked to instances of clinically apparent drug induced liver injury.

Esmolol hydrochloride

Esmolol hydrochloride

😃Good
Purity: 99.48%
Catalog No. T1503Alias Esmolol HCl, ASL8052Cas No. 81161-17-3
Esmolol is a cardioselective beta-blocker used in parenteral forms in the treatment of arrhythmias and severe hypertension. Esmolol has not been linked to instances of clinically apparent drug induced liver injury.
Pack SizePriceAvailabilityQuantity
25 mg$50Backorder
50 mg$72Backorder
1 mL x 10 mM (in DMSO)$50Backorder
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Purity:99.48%
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Product Introduction

Bioactivity
Description
Esmolol is a cardioselective beta-blocker used in parenteral forms in the treatment of arrhythmias and severe hypertension. Esmolol has not been linked to instances of clinically apparent drug induced liver injury.
In vitro
The main active site of Esmolol is the sinus node and AV node conduction system, and Esmolol has a rapid onset of action and inactivation.
In vivo
The main active site of Esmolol is the sinus node and AV node conduction system, and Esmolol has a rapid onset of action and inactivation.
AliasEsmolol HCl, ASL8052
Chemical Properties
Molecular Weight331.15
FormulaC16H25NO4·HCl
Cas No.81161-17-3
Smilesc1(ccc(cc1)CCC(=O)OC)OCC(CNC(C)C)O.Cl
Relative Density.1.026
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 198.9 mM
H2O: 150.68 mM
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM3.0198 mL15.0989 mL30.1978 mL150.9890 mL
5 mM0.6040 mL3.0198 mL6.0396 mL30.1978 mL
10 mM0.3020 mL1.5099 mL3.0198 mL15.0989 mL
20 mM0.1510 mL0.7549 mL1.5099 mL7.5494 mL
50 mM0.0604 mL0.3020 mL0.6040 mL3.0198 mL
100 mM0.0302 mL0.1510 mL0.3020 mL1.5099 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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