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FINO2

Catalog No. T60084Cas No. 869298-31-7

FINO2 is a potent ferroptosis-inducing compound that inhibits GPX4 activity. It functions as a stable oxidant, effectively oxidizing ferrous iron and demonstrating stability across varying pH levels. Furthermore, FINO2 induces widespread lipid peroxidation.

FINO2

FINO2

Purity: 97.27%
Catalog No. T60084Cas No. 869298-31-7
FINO2 is a potent ferroptosis-inducing compound that inhibits GPX4 activity. It functions as a stable oxidant, effectively oxidizing ferrous iron and demonstrating stability across varying pH levels. Furthermore, FINO2 induces widespread lipid peroxidation.
Pack SizePriceAvailabilityQuantity
1 mg$52In Stock
5 mg$129In Stock
10 mg$213In Stock
25 mg$359In Stock
50 mg$533In Stock
100 mg$759In Stock
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Purity:97.27%
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Product Introduction

Bioactivity
Description
FINO2 is a potent ferroptosis-inducing compound that inhibits GPX4 activity. It functions as a stable oxidant, effectively oxidizing ferrous iron and demonstrating stability across varying pH levels. Furthermore, FINO2 induces widespread lipid peroxidation.
In vitro
FINO2 (10 µM; 24 h) induces ferroptosis in HT-1080 cells, demonstrating the iron dependency of lipid peroxidation [1].
Chemical Properties
Molecular Weight256.38
FormulaC15H28O3
Cas No.869298-31-7
Storage & Solubility Information
Storagestore at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 90 mg/mL (351 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.9005 mL19.5023 mL39.0046 mL195.0230 mL
5 mM0.7801 mL3.9005 mL7.8009 mL39.0046 mL
10 mM0.3900 mL1.9502 mL3.9005 mL19.5023 mL
20 mM0.1950 mL0.9751 mL1.9502 mL9.7512 mL
50 mM0.0780 mL0.3900 mL0.7801 mL3.9005 mL
100 mM0.0390 mL0.1950 mL0.3900 mL1.9502 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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