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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $43 | In Stock | |
10 mg | $68 | In Stock | |
25 mg | $126 | In Stock | |
50 mg | $197 | In Stock | |
100 mg | $292 | In Stock | |
1 mL x 10 mM (in DMSO) | $48 | In Stock |
Description | Genz 123346 is an inhibitor of GL1 synthase that blocks the conversion of ceramide to GL1. |
Targets&IC50 | GM1:14 nM. |
In vivo | GLPG-1690 was able to cause a sustained reduction of LPA levels in plasma in vivo and was shown to be efficacious in a bleomycin-induced pulmonary fibrosis model in mice and in reducing extracellular matrix deposition in the lung while also reducing LPA 18:2 content in bronchoalveolar lavage fluid. |
Molecular Weight | 418.57 |
Formula | C24H38N2O4 |
Cas No. | 491833-30-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 50 mg/mL (119.45 mM) ![]() | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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