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Geranyl acetate

Catalog No. T5607Cas No. 105-87-3

Geranyl acetate is a monoterpene that has been found in C. sativa with diverse biological activities.

Geranyl acetate

Geranyl acetate

Purity: 99.36%
Catalog No. T5607Cas No. 105-87-3
Geranyl acetate is a monoterpene that has been found in C. sativa with diverse biological activities.
Pack SizePriceAvailabilityQuantity
5 g$31In Stock
1 mL x 10 mM (in DMSO)$39In Stock
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Purity:99.36%
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Product Introduction

Bioactivity
Description
Geranyl acetate is a monoterpene that has been found in C. sativa with diverse biological activities.
In vitro
Studies on the antifungal activity especially Microsporum gypsum, Trichophyton vercossum and Candida tropicalis showed that geranyl acetate, its epoxide and hydroperoxide derivatives have good antifungal action[1].Geranyl acetate exhibited significant anticancer activity against colo-205 cancer cell line with IC50 values of 30 μM . To find out the underlying mechanism, DAPI staining was carried out and it was observed that both the monoterpenes, geraniol and geranyl acetate, induced apoptosis in colo-205 cells. The apoptosis was also associated with upregulation of Bax and downregulation of Bcl-2 expressions, indicative of mitochondrial apoptosis. Moreover, this monoterpenes could trigger DNA damage and G2/M cell cycle arrest in colo-205 cells[1].
Cell Research
The antiproliferative activity was determined by MTT assay. Apoptosis was assessed by DAPI staining and DNA damage was checked by comet assay. The cell cycle analysis was carried out by flow cytometry and protein expression was examined by western blotting.[1].
Chemical Properties
Molecular Weight196.29
FormulaC12H20O2
Cas No.105-87-3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 25 mg/mL (127.36 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM5.0945 mL25.4725 mL50.9450 mL254.7252 mL
5 mM1.0189 mL5.0945 mL10.1890 mL50.9450 mL
10 mM0.5095 mL2.5473 mL5.0945 mL25.4725 mL
20 mM0.2547 mL1.2736 mL2.5473 mL12.7363 mL
50 mM0.1019 mL0.5095 mL1.0189 mL5.0945 mL
100 mM0.0509 mL0.2547 mL0.5095 mL2.5473 mL

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