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GSK3β inhibitor II

🥰Excellent
Catalog No. T21956Cas No. 478482-75-6

GSK3β inhibitor II is a GSK3β inhibitor. GSK3β inhibitor II exhibits the research potential of Alzheimer's disease (AD).

GSK3β inhibitor II

GSK3β inhibitor II

🥰Excellent
Purity: 99.32%
Catalog No. T21956Cas No. 478482-75-6
GSK3β inhibitor II is a GSK3β inhibitor. GSK3β inhibitor II exhibits the research potential of Alzheimer's disease (AD).
Pack SizePriceAvailabilityQuantity
10 mg$45In Stock
25 mg$96In Stock
50 mg$163In Stock
100 mg$223In Stock
1 mL x 10 mM (in DMSO)$30In Stock
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Purity:99.32%
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Product Introduction

Bioactivity
Description
GSK3β inhibitor II is a GSK3β inhibitor. GSK3β inhibitor II exhibits the research potential of Alzheimer's disease (AD).
In vitro
GSK3 β Inhibitor II exhibits hydrophobic interactions with Ile62, Phe67, Val70, Ala83, and Leu188, ionic interactions with Lys85, and hydrogen bonding interactions with Lys85 and Val135 residues. GSK3 β Inhibitor II forms a hydrogen bond with Val135 [1].
Chemical Properties
Molecular Weight395.22
FormulaC14H10IN3OS
Cas No.478482-75-6
SmilesIc1cccc(CSc2nnc(o2)-c2ccncc2)c1
Relative Density.1.79 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 5.5 mg/mL (13.92 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5302 mL12.6512 mL25.3024 mL126.5118 mL
5 mM0.5060 mL2.5302 mL5.0605 mL25.3024 mL
10 mM0.2530 mL1.2651 mL2.5302 mL12.6512 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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