Shopping Cart

Remove All

Your shopping cart is currently empty

HDAC8-IN-1

Select Batch

Purity:99.83%

Resource Download

COA HPLC HNMR LCMS

HDAC8-IN-1

Catalog No. T7082Cas No. 1417997-93-3

MDK-7933 (HDAC8-IN-1) is a HDAC8 inhibitor with an IC50 of 27.2 nM in cancer cell lines. MDK-7933 shows antiproliferative effects toward several human lung cancer cell lines (A549, H1299, and CL1-5). HDAC8-IN-1 exhibits cytotoxicity against human lung CL1-5 cells without significant cytotoxicity for normal IMR-90 cells[1].

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
2 mg	$66	In Stock
5 mg	$101	In Stock
10 mg	$154	In Stock
25 mg	$309	In Stock
50 mg	$479	In Stock
100 mg	$611	In Stock
1 mL x 10 mM (in DMSO)	$112	In Stock

Bulk & Custom

Add to Cart

Questions

Related Compound Libraries of "HDAC8-IN-1"

Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	345.39
Formula	C22H19NO3
Cas No.	1417997-93-3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 55 mg/mL (159.24 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8953 mL	14.4764 mL	28.9528 mL	144.7639 mL
5 mM	0.5791 mL	2.8953 mL	5.7906 mL	28.9528 mL
10 mM	0.2895 mL	1.4476 mL	2.8953 mL	14.4764 mL
20 mM	0.1448 mL	0.7238 mL	1.4476 mL	7.2382 mL
50 mM	0.0579 mL	0.2895 mL	0.5791 mL	2.8953 mL
100 mM	0.0290 mL	0.1448 mL	0.2895 mL	1.4476 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc