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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $290 | In Stock | |
5 mg | $664 | In Stock | |
10 mg | $930 | In Stock | |
25 mg | $1,310 | In Stock | |
50 mg | $1,640 | In Stock | |
100 mg | $1,995 | In Stock |
Description | icFSP1 is a mitochondria-associated apoptosis-inducing factor regulator with antitumor activity for the study and treatment of tumor diseases. |
In vitro | icFSP1(5 µM) triggers subcellular relocalization of FSP1 from the membrane and FSP1 condensation before ferroptosis induction, in synergism with GPX4 inhibition[1]. |
In vivo | In a tumour-bearing mouse model, icFSP1(i.p.) significantly inhibited tumour growth and decreased tumour weight, without affecting body weight. icFSP1 markedly increased the abundance of hFSP1 condensates and immunoreactivity to 4-hydroxynonenal, a lipid peroxidation breakdown product[1]. |
Molecular Weight | 459.49 |
Formula | C26H25N3O5 |
Cas No. | 1115910-36-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 55 mg/mL (119.7 mM) ![]() | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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