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icFSP1
🥰Excellent
Catalog No. T77344Cas No. 1115910-36-5
icFSP1 is a mitochondria-associated apoptosis-inducing factor regulator with antitumor activity for the study and treatment of tumor diseases.
icFSP1
🥰Excellent
Purity: 99.12%
Catalog No. T77344Cas No. 1115910-36-5
icFSP1 is a mitochondria-associated apoptosis-inducing factor regulator with antitumor activity for the study and treatment of tumor diseases.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $290 | In Stock | |
| 5 mg | $664 | In Stock | |
| 10 mg | $930 | In Stock | |
| 25 mg | $1,310 | In Stock | |
| 50 mg | $1,640 | In Stock | |
| 100 mg | $1,995 | In Stock |
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Purity:99.12%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | icFSP1 is a mitochondria-associated apoptosis-inducing factor regulator with antitumor activity for the study and treatment of tumor diseases. |
| In vitro | icFSP1(5 µM) triggers subcellular relocalization of FSP1 from the membrane and FSP1 condensation before ferroptosis induction, in synergism with GPX4 inhibition[1]. |
| In vivo | In a tumour-bearing mouse model, icFSP1(i.p.) significantly inhibited tumour growth and decreased tumour weight, without affecting body weight. icFSP1 markedly increased the abundance of hFSP1 condensates and immunoreactivity to 4-hydroxynonenal, a lipid peroxidation breakdown product[1]. |
| Molecular Weight | 459.49 |
| Formula | C26H25N3O5 |
| Cas No. | 1115910-36-5 |
| Smiles | O=C1N(C(C)=NC=2C1=CC=CC2)C3=CC=C(NC(CC4=CC(OC)=C(OC)C(OC)=C4)=O)C=C3 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 55 mg/mL (119.7 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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