Shopping Cart

Remove All

Your shopping cart is currently empty

Indobufen

Select Batch

Purity:99.73%

Resource Download

COA HPLC HNMR

Indobufen

Catalog No. T15577Cas No. 63610-08-2

Indobufen (Ibustrin) is an inhibitor of platelet aggregation and is a reversible platelet cyclooxygenase (Cox) activity inhibitor. Indobufen suppresses thromboxane A2 (TxA2) synthesis. Indobufen down-regulates tissue factor (TF) in monocytes.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
5 mg	$31	In Stock
10 mg	$48	In Stock
25 mg	$78	In Stock
50 mg	$113	In Stock
100 mg	$158	In Stock
200 mg	$236	In Stock
500 mg	$392	In Stock
1 mL x 10 mM (in DMSO)	$35	In Stock

Bulk & Custom

Add to Cart

Questions

Related Compound Libraries of "Indobufen"

Product Introduction

Bioactivity

Description	Indobufen (Ibustrin) is an inhibitor of platelet aggregation and is a reversible platelet cyclooxygenase (Cox) activity inhibitor. Indobufen suppresses thromboxane A2 (TxA2) synthesis. Indobufen down-regulates tissue factor (TF) in monocytes.
In vitro	Indobufen suppresses TxA2 but not PGE2 synthesis in LPS-stimulated monocytes. Indobufen causes the extent of ERK1/2 phosphorylation, whereas the levels of phosphorylated p38 are unaltered. Indobufen does not affect both Cox-1 and Cox-2 protein, whereas Indobufen reduces TxB2 levels.
Alias	Ibustrin

Chemical Properties

Molecular Weight	295.33
Formula	C18H17NO3
Cas No.	63610-08-2

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 55 mg/mL (186.23 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3860 mL	16.9302 mL	33.8604 mL	169.3021 mL
5 mM	0.6772 mL	3.3860 mL	6.7721 mL	33.8604 mL
10 mM	0.3386 mL	1.6930 mL	3.3860 mL	16.9302 mL
20 mM	0.1693 mL	0.8465 mL	1.6930 mL	8.4651 mL
50 mM	0.0677 mL	0.3386 mL	0.6772 mL	3.3860 mL
100 mM	0.0339 mL	0.1693 mL	0.3386 mL	1.6930 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc