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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $41 | In Stock | |
50 mg | $66 | In Stock | |
100 mg | $97 | In Stock | |
1 mL x 10 mM (in DMSO) | $45 | In Stock |
Description | Isoimperatorin is an anti-inflammatory agent, exhibits significant inhibitory effects on acetylcholinesterase (AChE). |
Targets&IC50 | AChE:74.6 μM. |
In vitro | The ethanol extract from Notopterygium incisum rhizomes displays significant nematicidal activity against nematodes Bursaphelenchus xylophilus and Meloidogyne incognita, discovered during a search for new agrochemicals from Chinese medicinal herbs. Four components—Columbianetin, Falcarindiol, Falcarinol, and Isoimperatorin—were isolated and identified from the extract via bioactivity-guided fractionation. Isoimperatorin exhibited notable efficacy with an LC50 value of 21.83 μg/mL against B. xylophilus. Under 15 min UV light exposure, Falcarindiol, Falcarinol, and Isoimperatorin showed nearly quintuple toxicity increase toward southern root-knot nematodes compared to dark conditions, whereas Columbianetin's toxicity doubled. Additionally, Isoimperatorin has been proven to have insecticidal properties against various insects, including the cabbage aphid (Brevicoryne brassicae). It has been found in the active fraction of Angelica dahurica (AD) extract and is frequently used as the internal standard (IS) in assays. |
Molecular Weight | 270.28 |
Formula | C16H14O4 |
Cas No. | 482-45-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | DMSO: 10 mg/mL (37 mM), Sonication is recommended. ![]() | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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