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JG26 is a potent inhibitor of ADAM17, which can inhibit ADAM8, ADAM17, ADAM10 and MMP-12, with IC50 values of 12 nM, 1.9 nM, 150 nM and 9.4 nM, respectively, and can be used to study the immune system of the body.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $83 | In Stock | |
5 mg | $198 | In Stock | |
10 mg | $297 | In Stock | |
25 mg | $523 | In Stock | |
50 mg | Inquiry | In Stock |
Description | JG26 is a potent inhibitor of ADAM17, which can inhibit ADAM8, ADAM17, ADAM10 and MMP-12, with IC50 values of 12 nM, 1.9 nM, 150 nM and 9.4 nM, respectively, and can be used to study the immune system of the body. |
Targets&IC50 | ADAM10:150 nM (IC50), MMP12:9.4 nM (IC50), MMP14:19500 nM (IC50), MMP8:240 nM (IC50), ADAM17:1.9 nM (IC50), MMP9:1630 nM (IC50), MMP9:>500000 nM (IC50), ADAM8:12 nM (IC50) |
Alias | JG-26, JG 26 |
Molecular Weight | 594.27 |
Formula | C19H22Br2N4O6S |
Cas No. | 1464910-32-4 |
Smiles | S(N[C@H](CCCNC(N)=O)C(NO)=O)(=O)(=O)C1=CC=C(OCC2=CC(Br)=CC(Br)=C2)C=C1 |
Relative Density. | 1.683 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 50 mg/mL (84.14 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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