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JNJ-39220675

TargetMol
Catalog No. T27678Cas No. 959740-39-7
Alias JNJ39220675, JNJ 39220675

JNJ-39220675 (JNJ 39220675) is a selective and brain permeable histamine H3 receptor antagonist.

JNJ-39220675

JNJ-39220675

TargetMol
Purity: 99.78%
Catalog No. T27678Alias JNJ39220675, JNJ 39220675Cas No. 959740-39-7
JNJ-39220675 (JNJ 39220675) is a selective and brain permeable histamine H3 receptor antagonist.
Pack SizePriceAvailabilityQuantity
1 mg$293In Stock
5 mg$722In Stock
10 mg$987In Stock
25 mg$1,520In Stock
50 mg$1,980In Stock
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Purity:99.78%
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Product Introduction

Bioactivity
Description
JNJ-39220675 (JNJ 39220675) is a selective and brain permeable histamine H3 receptor antagonist.
In vivo
After establishing a reliable baseline of alcohol and water intake, systemic (subcutaneous) administration of three doses of JNJ 39220675 (0.3, 3, and 10 mg/kg) to rats in the morning (10:00 AM) significantly and dose-dependently reduced alcohol self-administration without altering saccharin self-administration in alcohol-independent rats.
AliasJNJ39220675, JNJ 39220675
Chemical Properties
Molecular Weight369.43
FormulaC21H24FN3O2
Cas No.959740-39-7
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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