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Landipirdine

🥰Excellent
Catalog No. T27795Cas No. 1000308-25-7
Alias SYN-120, SYN120, SYN 120, RO-5025181, RO5025181, RO 5025181

Landipirdine (RO-5025181) is a selective 5-HT6R antagonist for the study of central nervous system disorders such as dementia.

Landipirdine

Landipirdine

🥰Excellent
Purity: 99.33%
Catalog No. T27795Alias SYN-120, SYN120, SYN 120, RO-5025181, RO5025181, RO 5025181Cas No. 1000308-25-7
Landipirdine (RO-5025181) is a selective 5-HT6R antagonist for the study of central nervous system disorders such as dementia.
Pack SizePriceAvailabilityQuantity
1 mg$247In Stock
5 mg$591In Stock
10 mg$793In Stock
25 mg$1,280In Stock
50 mg$1,630In Stock
100 mg$2,320In Stock
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Purity:99.33%
ee:100%
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Product Introduction

Bioactivity
Description
Landipirdine (RO-5025181) is a selective 5-HT6R antagonist for the study of central nervous system disorders such as dementia.
AliasSYN-120, SYN120, SYN 120, RO-5025181, RO5025181, RO 5025181
Chemical Properties
Molecular Weight362.42
FormulaC18H19FN2O3S
Cas No.1000308-25-7
SmilesC(NC(N)=O)[C@H]1C=2C(=CC(S(=O)(=O)C3=CC(F)=CC=C3)=CC2)CCC1
Relative Density.1.313 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 45 mg/mL (124.17 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.7592 mL13.7961 mL27.5923 mL137.9615 mL
5 mM0.5518 mL2.7592 mL5.5185 mL27.5923 mL
10 mM0.2759 mL1.3796 mL2.7592 mL13.7961 mL
20 mM0.1380 mL0.6898 mL1.3796 mL6.8981 mL
50 mM0.0552 mL0.2759 mL0.5518 mL2.7592 mL
100 mM0.0276 mL0.1380 mL0.2759 mL1.3796 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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