Shopping Cart
- Remove All
Your shopping cart is currently empty
Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $34 | 5 days |
Description | Lanicemine (AZD6765) dihydrochloride is a low-trapping blocker of the NMDA channel with Ki of 0.56-2.1 μM for NMDA receptor and IC 50s of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively. Lanicemine (AZD6765) dihydrochloride has sustained antidepressant efficacy [1]. |
In vivo | Lanicemine is a low-trapping NMDA channel blocker that produces sustained antidepressant efficacy with minimal psychotomimetic adverse effects[1]. Lanicemine (3, 10 or 30 mg/kg; intraperitoneal) not only engages brain circuits that generate the gamma- electroencephalography (EEG), but affects these networks without the broader systems-level disruptions typical of ketamine [1]. Animal Model: Male Sprague-Dawley rats [1] Dosage: 3, 10 or 30 mg/kg Administration: Intraperitoneal Result: A clear dose-dependent elevation in spontaneous gamma-band EEG was produced, but only gamma changes for Ketamine were strongly associated with increases in locomotor activity. |
Molecular Weight | 271.19 |
Formula | C13H16Cl2N2 |
Cas No. | 153322-06-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.