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LY450108

🥰Excellent
Catalog No. TQ0289Cas No. 376594-67-1

LY450108 is a potentiator of the AMPA receptor that can be used in Parkinson's disease studies.

LY450108

LY450108

🥰Excellent
Purity: 100%
Catalog No. TQ0289Cas No. 376594-67-1
LY450108 is a potentiator of the AMPA receptor that can be used in Parkinson's disease studies.
Pack SizePriceAvailabilityQuantity
2 mg$33In Stock
5 mg$53In Stock
10 mg$86In Stock
25 mg$148In Stock
50 mg$223In Stock
100 mg$311In Stock
200 mg$495In Stock
1 mL x 10 mM (in DMSO)$59In Stock
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Purity:100%
ee:97.94%
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Product Introduction

Bioactivity
Description
LY450108 is a potentiator of the AMPA receptor that can be used in Parkinson's disease studies.
Chemical Properties
Molecular Weight396.45
FormulaC19H22F2N2O3S
Cas No.376594-67-1
SmilesCC(C)S(=O)(=O)NC[C@H](C)c1ccc(NC(=O)c2cc(F)cc(F)c2)cc1
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (126.12 mM)
H2O: 1 mg/mL (2.52 mM), Sonication and heating are recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM2.5224 mL12.6119 mL25.2239 mL126.1193 mL
DMSO
1mg5mg10mg50mg
5 mM0.5045 mL2.5224 mL5.0448 mL25.2239 mL
10 mM0.2522 mL1.2612 mL2.5224 mL12.6119 mL
20 mM0.1261 mL0.6306 mL1.2612 mL6.3060 mL
50 mM0.0504 mL0.2522 mL0.5045 mL2.5224 mL
100 mM0.0252 mL0.1261 mL0.2522 mL1.2612 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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