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MC4033 is a selective lysine acetyltransferase 8 (KAT8) inhibitor (IC50: 12.1 μM) with anticancer effects, induces apoptosis, and can be used for the study of non-small cell lung cancer.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $31 | In Stock | |
5 mg | $70 | In Stock | |
10 mg | $113 | In Stock | |
25 mg | $229 | In Stock | |
50 mg | $372 | In Stock | |
100 mg | $596 | In Stock | |
500 mg | $1,250 | In Stock |
Description | MC4033 is a selective lysine acetyltransferase 8 (KAT8) inhibitor (IC50: 12.1 μM) with anticancer effects, induces apoptosis, and can be used for the study of non-small cell lung cancer. |
Targets&IC50 | KAT8:12.1 μM |
In vitro | MC4033 (10, 25, 50, and 100 μM; 72 hours) exhibited dose-dependent antiproliferative effects in HCT116, H1299, A549, and U937 cell lines. In U937 cells, the inhibition rate of cell proliferation was 70% at 50 μM and >80% at 100 μM[1]. |
Molecular Weight | 295.29 |
Formula | C16H13N3O3 |
Cas No. | 28532-21-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 15 mg/mL (50.80 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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