Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

MC4033

Catalog No. T78156Cas No. 28532-21-0

MC4033 is a selective lysine acetyltransferase 8 (KAT8) inhibitor (IC50: 12.1 μM) with anticancer effects, induces apoptosis, and can be used for the study of non-small cell lung cancer.

MC4033

MC4033

Purity: 98.16%
Catalog No. T78156Cas No. 28532-21-0
MC4033 is a selective lysine acetyltransferase 8 (KAT8) inhibitor (IC50: 12.1 μM) with anticancer effects, induces apoptosis, and can be used for the study of non-small cell lung cancer.
Pack SizePriceAvailabilityQuantity
1 mg$31In Stock
5 mg$70In Stock
10 mg$113In Stock
25 mg$229In Stock
50 mg$372In Stock
100 mg$596In Stock
500 mg$1,250In Stock
Bulk & Custom
Add to Cart
Questions
View More

Related Compound Libraries of "MC4033"

Select Batch
Purity:98.16%
Contact us for more batch information
Resource Download
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
MC4033 is a selective lysine acetyltransferase 8 (KAT8) inhibitor (IC50: 12.1 μM) with anticancer effects, induces apoptosis, and can be used for the study of non-small cell lung cancer.
Targets&IC50
KAT8:12.1 μM
In vitro
MC4033 (10, 25, 50, and 100 μM; 72 hours) exhibited dose-dependent antiproliferative effects in HCT116, H1299, A549, and U937 cell lines. In U937 cells, the inhibition rate of cell proliferation was 70% at 50 μM and >80% at 100 μM[1].
Chemical Properties
Molecular Weight295.29
FormulaC16H13N3O3
Cas No.28532-21-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 15 mg/mL (50.80 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3865 mL16.9325 mL33.8650 mL169.3251 mL
5 mM0.6773 mL3.3865 mL6.7730 mL33.8650 mL
10 mM0.3387 mL1.6933 mL3.3865 mL16.9325 mL
20 mM0.1693 mL0.8466 mL1.6933 mL8.4663 mL
50 mM0.0677 mL0.3387 mL0.6773 mL3.3865 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy MC4033 | purchase MC4033 | MC4033 cost | order MC4033 | MC4033 chemical structure | MC4033 in vitro | MC4033 formula | MC4033 molecular weight