Shopping Cart

Remove All

Your shopping cart is currently empty

Mequitazine

Select Batch

Purity:99.95%

Resource Download

COA HNMR HPLC LCMS

Mequitazine

Catalog No. T4499Cas No. 29216-28-2

Mequitazine (Virginan) is an effective, nonsedative and long-acting histamine H1 antagonist.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
5 mg	$42	In Stock
10 mg	$58	In Stock
25 mg	$91	In Stock
50 mg	$124	In Stock
100 mg	$156	In Stock
1 mL x 10 mM (in DMSO)	$46	In Stock

Bulk & Custom

Add to Cart

Questions

Related Compound Libraries of "Mequitazine"

Product Introduction

Bioactivity

Description	Mequitazine (Virginan) is an effective, nonsedative and long-acting histamine H1 antagonist.
In vitro	Mequitazine is widely studied and used for allergic disorders such as hay fever and urticaria[1]. Mequitazine demonstrates significant bactericidal effects against all the tested clinical isolates including Ps. aeruginosa. Its effect against the Gram-positive isolates is more pronounced [2].
In vivo	Mequitazine antagonizes the effect of histamine in guinea-pig ileum competitively. Mequitazine at 107 produces a parallel shift of the dose-response curve to acetylcholine in the rat duodenum. Mequitazine at highest concentration shows anticholinergic activity [3]. Mequitazine inhibits contractile responses to KCl, phenylephrine (PE), 5-hydroxytryptamine (5-HT), and Ca2+ in rat aorta [4].
Alias	Metaplexan, Virginan, Primalan, LM-209

Chemical Properties

Molecular Weight	322.47
Formula	C20H22N2S
Cas No.	29216-28-2

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 50 mg/mL (155.05 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.1011 mL	15.5053 mL	31.0106 mL	155.0532 mL
5 mM	0.6202 mL	3.1011 mL	6.2021 mL	31.0106 mL
10 mM	0.3101 mL	1.5505 mL	3.1011 mL	15.5053 mL
20 mM	0.1551 mL	0.7753 mL	1.5505 mL	7.7527 mL
50 mM	0.0620 mL	0.3101 mL	0.6202 mL	3.1011 mL
100 mM	0.0310 mL	0.1551 mL	0.3101 mL	1.5505 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc