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MID-1

MID-1
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Purity:99.61%
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MID-1

Catalog No. T8773Cas No. 312608-54-1
MID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction. It disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake
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Pack SizePriceAvailabilityQuantity
1 mg$76In Stock
5 mg$163In Stock
10 mg$247In Stock
25 mg$455In Stock
50 mg$672In Stock
100 mg$956In Stock
500 mg$1,920In Stock
1 mL x 10 mM (in DMSO)$185In Stock
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Product Introduction

Bioactivity
Description
MID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction. It disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake
Chemical Properties
Molecular Weight293.3
FormulaC12H11N3O4S
Cas No.312608-54-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 4.5 mg/mL (15.34 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.4095 mL17.0474 mL34.0948 mL170.4739 mL
5 mM0.6819 mL3.4095 mL6.8190 mL34.0948 mL
10 mM0.3409 mL1.7047 mL3.4095 mL17.0474 mL

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