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ML277
Catalog No. T3303Cas No. 1401242-74-7
ML277 (CID-53347902) was identified as a potent activator of KCNQ1 channels (EC(50)=260 nM).
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $34 | In Stock | |
| 5 mg | $71 | In Stock | |
| 10 mg | $132 | In Stock | |
| 25 mg | $245 | In Stock | |
| 50 mg | $453 | In Stock | |
| 100 mg | $667 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $91 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | ML277 (CID-53347902) was identified as a potent activator of KCNQ1 channels (EC(50)=260 nM). |
| In vitro | ML277(CID53347902) is a novel, potent and selective K(v)7.1 (KCNQ1) potassium channel activator with EC50 of 270 nM. IC50 value: 270 nM (EC50) [1] Target: K(v)7.1 activator ML277 was shown to be highly selective against other KCNQ channels (>100-fold selectivity versus KCNQ2 and KCNQ4) as well as against the distantly related hERG potassium channel[1]. |
| Alias | ML-277, CID-53347902 |
| Molecular Weight | 471.59 |
| Formula | C23H25N3O4S2 |
| Cas No. | 1401242-74-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 60 mg/mL (127.23 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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