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Niridazole

🥰Excellent
Catalog No. T28174Cas No. 61-57-4
Alias BA-32644, BA32644, BA 32644, Ambilhar

Niridazole (Ambilhar) is an antiparasitic compound belonging to nitroimidazoles. Niridazole is primarily used to treat schistosomiasis, which kills the parasite by interfering with its metabolism. Niridazole rapidly concentrates in the parasite, inhibits egg and sperm production, and inhibits phosphofructokinase activity.

Niridazole

Niridazole

🥰Excellent
Purity: 98.90%
Catalog No. T28174Alias BA-32644, BA32644, BA 32644, AmbilharCas No. 61-57-4
Niridazole (Ambilhar) is an antiparasitic compound belonging to nitroimidazoles. Niridazole is primarily used to treat schistosomiasis, which kills the parasite by interfering with its metabolism. Niridazole rapidly concentrates in the parasite, inhibits egg and sperm production, and inhibits phosphofructokinase activity.
Pack SizePriceAvailabilityQuantity
1 mg$397In Stock
5 mg$970In Stock
10 mg$1,290In Stock
25 mg$1,950In Stock
50 mg$2,620In Stock
100 mg$3,530In Stock
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Purity:98.90%
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Product Introduction

Bioactivity
Description
Niridazole (Ambilhar) is an antiparasitic compound belonging to nitroimidazoles. Niridazole is primarily used to treat schistosomiasis, which kills the parasite by interfering with its metabolism. Niridazole rapidly concentrates in the parasite, inhibits egg and sperm production, and inhibits phosphofructokinase activity.
In vitro
The minimum inhibitory concentrations for niridazole ranged from 0.0037 to 1.0 microgram/ml [1]
In vivo
Niridazole, a human anthelminthic drug, is shown to be a potent long-acting suppressor of delayed hypersensitivity. Much lower doses than used in the therapy of helminth infections suppressed granuloma formation around Schistosoma mansoni eggs for periods up to 32 days and inhibited delayed footpad swelling in mice previously sensitized with eggs. Marked prolongation of skin allograft survival in mice across the H-2 area was produced.[2]
AliasBA-32644, BA32644, BA 32644, Ambilhar
Chemical Properties
Molecular Weight214.2
FormulaC6H6N4O3S
Cas No.61-57-4
SmilesO=C1N(C=2SC(N(=O)=O)=CN2)CCN1
Relative Density.1.561 g/cm3 (Estimated)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 1 mg/mL, Sonication is recommended.

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