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Product Introduction

Bioactivity

Description	4-Carboxyquinoline (4-Quinolinecarboxylic acid) showed anti-tumor activity against L1210 leukemia and B16 melanoma.
Alias	QUINOLINE-4-CARBOXYLIC ACID, 4-Quinolinecarboxylic acid

Chemical Properties

Molecular Weight	173.17
Formula	C₁₀H₇NO₂
Cas No.	486-74-8

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 4.23 mg/mL (24.43 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.7747 mL	28.8734 mL	57.7467 mL	288.7336 mL
5 mM	1.1549 mL	5.7747 mL	11.5493 mL	57.7467 mL
10 mM	0.5775 mL	2.8873 mL	5.7747 mL	28.8734 mL
20 mM	0.2887 mL	1.4437 mL	2.8873 mL	14.4367 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

NSC13138Endogenous MetaboliteNSC 13138InhibitorinhibitCinchoninic acid (6CI,7CI,8CI)NSC-131384-Carboxyquinoline