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O-304

Catalog No. T7362Cas No. 1261289-04-6

O-304 is a pan-activator of AMP-activated protein kinase (AMPK).

O-304

O-304

Purity: 99.80%
Catalog No. T7362Cas No. 1261289-04-6
O-304 is a pan-activator of AMP-activated protein kinase (AMPK).
Pack SizePriceAvailabilityQuantity
1 mg$60In Stock
2 mg$88In Stock
5 mg$147In Stock
10 mg$228In Stock
25 mg$455In Stock
50 mg$672In Stock
100 mg$956In Stock
500 mg$1,920In Stock
1 mL x 10 mM (in DMSO)$162In Stock
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Purity:99.80%
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Product Introduction

Bioactivity
Description
O-304 is a pan-activator of AMP-activated protein kinase (AMPK).
In vivo
In vivo, O-304 (100 mg/kg) prevents high-fat diet-induced increases in fasted glucose and plasma insulin levels and development of insulin resistance, as well as increases calf muscle pAMPK levels in mice.
Chemical Properties
Molecular Weight380.25
FormulaC16H11Cl2N3O2S
Cas No.1261289-04-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 45 mg/mL (118.34 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.6298 mL13.1492 mL26.2985 mL131.4924 mL
5 mM0.5260 mL2.6298 mL5.2597 mL26.2985 mL
10 mM0.2630 mL1.3149 mL2.6298 mL13.1492 mL
20 mM0.1315 mL0.6575 mL1.3149 mL6.5746 mL
50 mM0.0526 mL0.2630 mL0.5260 mL2.6298 mL
100 mM0.0263 mL0.1315 mL0.2630 mL1.3149 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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