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ORL1 antagonist 1

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Catalog No. T12320Cas No. 1174985-59-1

ORL1 antagonist 1 is an o antagonist of pioid receptor-like 1 (ORL1) (IC50 of 61 nM).

ORL1 antagonist 1

ORL1 antagonist 1

🥰Excellent
Purity: 97.87%
Catalog No. T12320Cas No. 1174985-59-1
ORL1 antagonist 1 is an o antagonist of pioid receptor-like 1 (ORL1) (IC50 of 61 nM).
Pack SizePriceAvailabilityQuantity
1 mg$70In Stock
5 mg$161In Stock
10 mg$237In Stock
25 mg$355In Stock
50 mg$500In Stock
100 mg$672In Stock
200 mg$890In Stock
1 mL x 10 mM (in DMSO)$166In Stock
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Purity:97.87%
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Product Introduction

Bioactivity
Description
ORL1 antagonist 1 is an o antagonist of pioid receptor-like 1 (ORL1) (IC50 of 61 nM).
Targets&IC50
ORL1:61 nM
Chemical Properties
Molecular Weight367.88
FormulaC20H22ClN5
Cas No.1174985-59-1
SmilesCC1=C(N(N=C1CNC2CCCC2)C3=C(Cl)C=CC=N3)C=4C=CC=NC4
Relative Density.1.32 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/mL (149.51 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.7183 mL13.5914 mL27.1828 mL135.9139 mL
5 mM0.5437 mL2.7183 mL5.4366 mL27.1828 mL
10 mM0.2718 mL1.3591 mL2.7183 mL13.5914 mL
20 mM0.1359 mL0.6796 mL1.3591 mL6.7957 mL
50 mM0.0544 mL0.2718 mL0.5437 mL2.7183 mL
100 mM0.0272 mL0.1359 mL0.2718 mL1.3591 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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