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Pack Size | Price | Availability | Quantity |
---|---|---|---|
500 mg | $227 | Backorder |
Description | Oxythiamine is an antimetabolite and an antagonist of vitamin B1. |
In vitro | Oxythiamine (OT), an analogue of anti-metabolite, can suppress the nonoxidative synthesis of ribose and induce cell apoptosis by causing a G1 phase arrest in vitro and in vivo.Annexin A1 expression was significantly down-regulated by OT treatment in time-dependent manner, while no change of this protein was observed in OT dose-dependent fashion.?Pathway analysis suggested that inhibition of transketolase resulted in changes of multiple cellular signaling pathways associated with cell apoptosis. |
Alias | Hydroxythiamin |
Molecular Weight | 266.34 |
Formula | C12H16N3O2S |
Cas No. | 136-16-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 51.67 mg/mL (194.00 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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