Pardoprunox

Name: Pardoprunox
Brand: TargetMol
SKU: T1769
Price: 30 USD
Availability: InStock
Rating: 4.5 (1 reviews)

Catalog No. T1769Cas No. 269718-84-5

Alias SLV-308, DU-126891

Pardoprunox (SLV-308) is a partial dopamine D2 agonist and noradrenergic agonist with serotonin 5-HT1A agonist properties, used in trials for treating Early Stage Parkinson's Disease and Advanced Stage Parkinson's Disease.

Pardoprunox

Catalog No. T1769Alias SLV-308, DU-126891Cas No. 269718-84-5

Pack Size	Price	Availability	Quantity
25 mg	$887	4-6 weeks

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COA

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	Pardoprunox (SLV-308) is a partial dopamine D2 agonist and noradrenergic agonist with serotonin 5-HT1A agonist properties, used in trials for treating Early Stage Parkinson's Disease and Advanced Stage Parkinson's Disease.
Targets&IC50	D3:8.6(pKi), D2:8.1(pKi)
Alias	SLV-308, DU-126891

Chemical Properties

Molecular Weight	233.27
Formula	C₁₂H₁₅N₃O₂
Cas No.	269718-84-5

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 10 mM

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.2869 mL	21.4344 mL	42.8688 mL	214.3439 mL
5 mM	0.8574 mL	4.2869 mL	8.5738 mL	42.8688 mL
10 mM	0.4287 mL	2.1434 mL	4.2869 mL	21.4344 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc