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Phosalone

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Purity:98%

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COA HNMR

Phosalone

Catalog No. T5839Cas No. 2310-17-0

Phosalone is an organophosphate chemical commonly used as an insecticide and acaricide.

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Pack Size	Price	Availability	Quantity
500 mg	$42	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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Product Introduction

Bioactivity

Description

Phosalone is an organophosphate chemical commonly used as an insecticide and acaricide.

In vivo

Phosalone (PLN) as a key member of OPs, to induce senescence in rat embryonic fibroblast (REF) cells and to demonstrate the beneficial effects of the known antioxidant ellagic acid (EA) in diminishing the PLN-induced toxic effects, the levels of cell viability, oxidative stress markers, inflammatory cytokines, telomerase activity, and the expression of the genes related to senescence were investigated. This accounts for the mechanistic approval of the role of OPs in induction of senescence in rat fibroblasts. Incorporation of EA diminished PLN toxicity mainly through suppression of p38 and p53 at gene and protein levels, and tempered the inflammation factors (TNF-α, IL-1β, IL-6 and NF-κB), which further affected cell division.

Chemical Properties

Molecular Weight	367.81
Formula	C12H15ClNO4PS2
Cas No.	2310-17-0

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL (135.94 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7188 mL	13.5940 mL	27.1880 mL	135.9398 mL
5 mM	0.5438 mL	2.7188 mL	5.4376 mL	27.1880 mL
10 mM	0.2719 mL	1.3594 mL	2.7188 mL	13.5940 mL
20 mM	0.1359 mL	0.6797 mL	1.3594 mL	6.7970 mL
50 mM	0.0544 mL	0.2719 mL	0.5438 mL	2.7188 mL
100 mM	0.0272 mL	0.1359 mL	0.2719 mL	1.3594 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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