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Polygalacic acid

Polygalacic acid
Polygalacic acid (Virgaureagenin G)(PA) significantly improves cholinergic system reactivity, as indicated by decreased acetylcholinesterase (AChE) activity, increases choline acetyltransferase (ChAT) activity, and elevates levels of acetylcholine (ACh) in the hippocampus and frontal cortex, PA also significantly ameliorates neuroinflammation and oxidative stress in mice; suggest that PA might exert a significant neuroprotective effect on cognitive impairment, driven in part by the modulation of cholinergic activity and neuroinflammation. Polygalacic acid shows significant postingestive effects on Spodoptera littoralis larvae.
Catalog No. T3767Cas No. 22338-71-2
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Purity:98.92%
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Polygalacic acid

Catalog No. T3767Cas No. 22338-71-2
Polygalacic acid (Virgaureagenin G)(PA) significantly improves cholinergic system reactivity, as indicated by decreased acetylcholinesterase (AChE) activity, increases choline acetyltransferase (ChAT) activity, and elevates levels of acetylcholine (ACh) in the hippocampus and frontal cortex, PA also significantly ameliorates neuroinflammation and oxidative stress in mice; suggest that PA might exert a significant neuroprotective effect on cognitive impairment, driven in part by the modulation of cholinergic activity and neuroinflammation. Polygalacic acid shows significant postingestive effects on Spodoptera littoralis larvae.
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Product Introduction

Bioactivity
Description
Polygalacic acid (Virgaureagenin G)(PA) significantly improves cholinergic system reactivity, as indicated by decreased acetylcholinesterase (AChE) activity, increases choline acetyltransferase (ChAT) activity, and elevates levels of acetylcholine (ACh) in the hippocampus and frontal cortex, PA also significantly ameliorates neuroinflammation and oxidative stress in mice; suggest that PA might exert a significant neuroprotective effect on cognitive impairment, driven in part by the modulation of cholinergic activity and neuroinflammation. Polygalacic acid shows significant postingestive effects on Spodoptera littoralis larvae.
AliasVirgaureagenin G
Chemical Properties
Molecular Weight504.7
FormulaC30H48O6
Cas No.22338-71-2
Storage & Solubility Information
Storagestore at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 91 mg/mL (180.3 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.9814 mL9.9069 mL19.8138 mL99.0688 mL
5 mM0.3963 mL1.9814 mL3.9628 mL19.8138 mL
10 mM0.1981 mL0.9907 mL1.9814 mL9.9069 mL
20 mM0.0991 mL0.4953 mL0.9907 mL4.9534 mL
50 mM0.0396 mL0.1981 mL0.3963 mL1.9814 mL
100 mM0.0198 mL0.0991 mL0.1981 mL0.9907 mL

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