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Quercetin 3-gentiobioside

Quercetin 3-gentiobioside
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Purity:99.77%
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Quercetin 3-gentiobioside

Catalog No. TN2122Cas No. 7431-83-6
Quercetin 3-gentiobioside (Quercetin-3-gentiobioside) is an inhibitor of AR and AGE formation and can be extracted from A. iwayomogi.Quercetin 3-gentiobioside inhibits the biological activity of aldose reductase (AR) and the formation of advanced glycosylation end products (AGEs).
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Pack SizePriceAvailabilityQuantity
1 mg$109In Stock
5 mg$276In Stock
10 mg$469In Stock
25 mg$759In Stock
50 mg$987In Stock
1 mL x 10 mM (in DMSO)$393In Stock
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Product Introduction

Bioactivity
Description
Quercetin 3-gentiobioside (Quercetin-3-gentiobioside) is an inhibitor of AR and AGE formation and can be extracted from A. iwayomogi.Quercetin 3-gentiobioside inhibits the biological activity of aldose reductase (AR) and the formation of advanced glycosylation end products (AGEs).
In vitro
We led to isolation of Quercetin-3-gentiobioside was first reported on the isolation from A. iwayomogi. A. iwayomogi extracts showed significant inhibitor on AR and AGEs formation activities[1]
We also determined quercetin 3-O-gentiobioside have antioxidant activity in vitro.[2]
In vivo
Treatment with quercetin 3-O-gentiobioside (HF diet-induced obese mice; 0.1% Iso and Que) reduced blood glucose and serum insulin levels and improved glucose tolerance in obese mice. Meanwhile, serum triglyceride levels and liver morphology in the mice were significantly ameliorated by EO and isoquercitrin treatment. Total cholesterol levels in quercetin 3-O-gentiobioside treated mice were also reduced.[2]
AliasQuercetin-3-gentiobioside
Chemical Properties
Molecular Weight626.52
FormulaC27H30O17
Cas No.7431-83-6
Storage & Solubility Information
Storagekeep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 90.0 mg/mL (143.6 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.5961 mL7.9806 mL15.9612 mL79.8059 mL
5 mM0.3192 mL1.5961 mL3.1922 mL15.9612 mL
10 mM0.1596 mL0.7981 mL1.5961 mL7.9806 mL
20 mM0.0798 mL0.3990 mL0.7981 mL3.9903 mL
50 mM0.0319 mL0.1596 mL0.3192 mL1.5961 mL
100 mM0.0160 mL0.0798 mL0.1596 mL0.7981 mL

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