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Quercetin 3-gentiobioside
🥰Excellent
Catalog No. TN2122Cas No. 7431-83-6
Alias Quercetin-3-gentiobioside
Quercetin 3-gentiobioside (Quercetin-3-gentiobioside) is an inhibitor of AR and AGE formation and can be extracted from A. iwayomogi.Quercetin 3-gentiobioside inhibits the biological activity of aldose reductase (AR) and the formation of advanced glycosylation end products (AGEs).
Quercetin 3-gentiobioside
🥰Excellent
Purity: 99.77%
Catalog No. TN2122Alias Quercetin-3-gentiobiosideCas No. 7431-83-6
Quercetin 3-gentiobioside (Quercetin-3-gentiobioside) is an inhibitor of AR and AGE formation and can be extracted from A. iwayomogi.Quercetin 3-gentiobioside inhibits the biological activity of aldose reductase (AR) and the formation of advanced glycosylation end products (AGEs).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $109 | In Stock | |
| 5 mg | $276 | In Stock | |
| 10 mg | $469 | In Stock | |
| 25 mg | $759 | In Stock | |
| 50 mg | $987 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $393 | In Stock |
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Purity:99.77%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Quercetin 3-gentiobioside (Quercetin-3-gentiobioside) is an inhibitor of AR and AGE formation and can be extracted from A. iwayomogi.Quercetin 3-gentiobioside inhibits the biological activity of aldose reductase (AR) and the formation of advanced glycosylation end products (AGEs). |
| Targets&IC50 | AR:10.6±0.38, AGE:109.46±1.41 |
| In vitro | We led to isolation of Quercetin-3-gentiobioside was first reported on the isolation from A. iwayomogi. A. iwayomogi extracts showed significant inhibitor on AR and AGEs formation activities[1] We also determined quercetin 3-O-gentiobioside have antioxidant activity in vitro.[2] |
| In vivo | Treatment with quercetin 3-O-gentiobioside (HF diet-induced obese mice; 0.1% Iso and Que) reduced blood glucose and serum insulin levels and improved glucose tolerance in obese mice. Meanwhile, serum triglyceride levels and liver morphology in the mice were significantly ameliorated by EO and isoquercitrin treatment. Total cholesterol levels in quercetin 3-O-gentiobioside treated mice were also reduced.[2] |
| Alias | Quercetin-3-gentiobioside |
| Molecular Weight | 626.52 |
| Formula | C27H30O17 |
| Cas No. | 7431-83-6 |
| Smiles | OC[C@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3c(oc4cc(O)cc(O)c4c3=O)-c3ccc(O)c(O)c3)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O |
| Relative Density. | 1.89 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 90.0 mg/mL (143.6 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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