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QX-222 chloride

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Catalog No. T23213Cas No. 5369-00-6
Alias QX 222 hloride, Lidocaine N-Methyl Hydrochloride

QX-222 chloride (Lidocaine N-Methyl Hydrochloride) is a sodium channel blocker.

QX-222 chloride

QX-222 chloride

🥰Excellent
Purity: 96.21%
Catalog No. T23213Alias QX 222 hloride, Lidocaine N-Methyl HydrochlorideCas No. 5369-00-6
QX-222 chloride (Lidocaine N-Methyl Hydrochloride) is a sodium channel blocker.
Pack SizePriceAvailabilityQuantity
10 mg$38In Stock
25 mg$74In Stock
50 mg$137In Stock
100 mg$223In Stock
200 mg$329In Stock
1 mL x 10 mM (in DMSO)$29In Stock
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Purity:96.21%
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Product Introduction

Bioactivity
Description
QX-222 chloride (Lidocaine N-Methyl Hydrochloride) is a sodium channel blocker.
In vivo
Intravenous infusion administration of 10 mg/kg QX-222 chloride for 7 days reverses spinal nerve ligation (SNL)-induced thermal hypersensitivity and induced antinociception in sham-operated rats[2].
AliasQX 222 hloride, Lidocaine N-Methyl Hydrochloride
Chemical Properties
Molecular Weight256.77
FormulaC13H21ClN2O
Cas No.5369-00-6
Smiles[Cl-].Cc1cccc(C)c1NC(=O)C[N+](C)(C)C
Relative Density.1.31g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (389.45 mM), Sonication and heating to 60℃ are recommended.
H2O: 100 mM
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM3.8945 mL19.4727 mL38.9454 mL194.7268 mL
5 mM0.7789 mL3.8945 mL7.7891 mL38.9454 mL
10 mM0.3895 mL1.9473 mL3.8945 mL19.4727 mL
20 mM0.1947 mL0.9736 mL1.9473 mL9.7363 mL
50 mM0.0779 mL0.3895 mL0.7789 mL3.8945 mL
100 mM0.0389 mL0.1947 mL0.3895 mL1.9473 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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