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Ro 67-7476

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Catalog No. T3478Cas No. 298690-60-5

Ro 67-7476 is a positive allosteric modulator of mGlu1 receptors. No activity at human mGlu1 receptors. Potentiates glutamate-induced calcium release with EC 50 of 60.1 nM.

Ro 67-7476

Ro 67-7476

🥰Excellent
Purity: 99.48%
Catalog No. T3478Cas No. 298690-60-5
Ro 67-7476 is a positive allosteric modulator of mGlu1 receptors. No activity at human mGlu1 receptors. Potentiates glutamate-induced calcium release with EC 50 of 60.1 nM.
Pack SizePriceAvailabilityQuantity
1 mg$30In Stock
2 mg$43In Stock
5 mg$85In Stock
10 mg$133In Stock
25 mg$271In Stock
50 mg$490In Stock
100 mg$715In Stock
1 mL x 10 mM (in DMSO)$75In Stock
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Purity:99.48%
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Product Introduction

Bioactivity
Description
Ro 67-7476 is a positive allosteric modulator of mGlu1 receptors. No activity at human mGlu1 receptors. Potentiates glutamate-induced calcium release with EC 50 of 60.1 nM.
Targets&IC50
mGluR1a:60.1 nM (EC50)
Chemical Properties
Molecular Weight319.39
FormulaC17H18FNO2S
Cas No.298690-60-5
SmilesCc1ccc(cc1)S(=O)(=O)N1CCC[C@H]1c1ccc(F)cc1
Relative Density.1.268 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (156.55 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.1310 mL15.6548 mL31.3097 mL156.5484 mL
5 mM0.6262 mL3.1310 mL6.2619 mL31.3097 mL
10 mM0.3131 mL1.5655 mL3.1310 mL15.6548 mL
20 mM0.1565 mL0.7827 mL1.5655 mL7.8274 mL
50 mM0.0626 mL0.3131 mL0.6262 mL3.1310 mL
100 mM0.0313 mL0.1565 mL0.3131 mL1.5655 mL

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