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Camonsertib

Camonsertib
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Purity:98.15%
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Camonsertib

Catalog No. T62083Cas No. 2417489-10-0
Camonsertib (RP-3500) is a selective, orally active ATR kinase inhibitor (ATRi) with an IC50: 1.00 nM in biochemical assays and exhibits potent antitumour effects. Camonsertib is 30 times more selective for ATR than mTOR (IC50: 120 nM) and is a more active inhibitor of ATM, DNA-PK and PI3Kα kinases. PK and PI3Kα kinases.
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Pack SizePriceAvailabilityQuantity
1 mg$208In Stock
5 mg$528In Stock
10 mg$769In Stock
25 mg$1,190In Stock
50 mg$1,580In Stock
100 mg$2,160In Stock
1 mL x 10 mM (in DMSO)$591In Stock
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Product Introduction

Bioactivity
Description
Camonsertib (RP-3500) is a selective, orally active ATR kinase inhibitor (ATRi) with an IC50: 1.00 nM in biochemical assays and exhibits potent antitumour effects. Camonsertib is 30 times more selective for ATR than mTOR (IC50: 120 nM) and is a more active inhibitor of ATM, DNA-PK and PI3Kα kinases. PK and PI3Kα kinases.
AliasATR inhibitor 4, RP-3500
Chemical Properties
Molecular Weight410.47
FormulaC21H26N6O3
Cas No.2417489-10-0
Storage & Solubility Information
Storagestore at low temperature,keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 45.0 mg/mL (109.6 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4362 mL12.1812 mL24.3623 mL121.8116 mL
5 mM0.4872 mL2.4362 mL4.8725 mL24.3623 mL
10 mM0.2436 mL1.2181 mL2.4362 mL12.1812 mL
20 mM0.1218 mL0.6091 mL1.2181 mL6.0906 mL
50 mM0.0487 mL0.2436 mL0.4872 mL2.4362 mL
100 mM0.0244 mL0.1218 mL0.2436 mL1.2181 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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