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Silperisone HCl

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Purity:99.62%

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COA LCMS HPLC FNMR HNMR

Silperisone HCl

Catalog No. T28778Cas No. 140944-30-5

Silperisone HCl (RGH-5002) blocks sodium and calcium channels in cells, decreases excitability and contractility of muscle cells, reduces peripheral tone, and acts as a muscle relaxant and peripheral vasodilator. Silperisone HCl is used to treat recurrent painful myoclonus due to spinal cord injury, abnormal hypertonia due to cerebrovascular disease, dystonia symptoms, cone tension syndrome, multiple sclerosis myospasm and myelitis. silperisone is a sodium channel protein type 2 alpha channel blocker. silperisone is an organosilicon similar to tolperisone, an organosilicon compound with centrally acting muscle relaxant properties.

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Pack Size	Price	Availability
1 mg	$133	In Stock
5 mg	$320	In Stock
10 mg	$480	In Stock
25 mg	$786	In Stock
50 mg	$1,080	In Stock
100 mg	$1,480	In Stock
500 mg	$2,960	In Stock

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Questions

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Product Introduction

Bioactivity

Description

Alias

RGH5002, SILA336, RGH-5002, Silperisone hydrochloride, SILA-336

Chemical Properties

Molecular Weight	301.9
Formula	C15H25ClFNSi
Cas No.	140944-30-5

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL (165.62 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3124 mL	16.5618 mL	33.1236 mL	165.6178 mL
5 mM	0.6625 mL	3.3124 mL	6.6247 mL	33.1236 mL
10 mM	0.3312 mL	1.6562 mL	3.3124 mL	16.5618 mL
20 mM	0.1656 mL	0.8281 mL	1.6562 mL	8.2809 mL
50 mM	0.0662 mL	0.3312 mL	0.6625 mL	3.3124 mL
100 mM	0.0331 mL	0.1656 mL	0.3312 mL	1.6562 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

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