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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $92 | In Stock | |
2 mg | $135 | In Stock | |
5 mg | $268 | In Stock | |
10 mg | $456 | In Stock | |
25 mg | $877 | In Stock | |
50 mg | $1,130 | In Stock | |
100 mg | $1,530 | In Stock |
Description | Snail/HDAC-IN-1 is a Snail/HDAC inhibitor agent with antimicrobial and anticancer activity, reduces Snail protein expression, induces apoptosis, and can be used in the study of solid tumors. |
In vitro | Snail/HDAC-IN-1 exhibited the most potent inhibitory activity against HDAC1 with an IC50 of 0.405 μM, potent inhibition against Snail with a Kd of 0.180 μM, and antiproliferative activity in HCT-116 cell lines with an IC50 of 0.0751 μM. Snail/HDAC-IN-1 showed good inhibitory effects on NCI-H522 (GI50 = 0.0488 μM), MDA-MB-435 (GI50 = 0.0361 μM), and MCF7 (GI50 = 0.0518 μM)[1]. |
Molecular Weight | 488.54 |
Formula | C24H21FN8OS |
Cas No. | 2415281-52-4 |
Storage | keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||
Solubility Information | DMSO: 100 mg/mL (20.47 mM) | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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