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Snail/HDAC-IN-1

Snail/HDAC-IN-1
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Snail/HDAC-IN-1

Catalog No. T63260Cas No. 2415281-52-4
Snail/HDAC-IN-1 is a Snail/HDAC inhibitor agent with antimicrobial and anticancer activity, reduces Snail protein expression, induces apoptosis, and can be used in the study of solid tumors.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
1 mg$92In Stock
2 mg$135In Stock
5 mg$268In Stock
10 mg$456In Stock
25 mg$877In Stock
50 mg$1,130In Stock
100 mg$1,530In Stock
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Product Introduction

Bioactivity
Description
Snail/HDAC-IN-1 is a Snail/HDAC inhibitor agent with antimicrobial and anticancer activity, reduces Snail protein expression, induces apoptosis, and can be used in the study of solid tumors.
In vitro
Snail/HDAC-IN-1 exhibited the most potent inhibitory activity against HDAC1 with an IC50 of 0.405 μM, potent inhibition against Snail with a Kd of 0.180 μM, and antiproliferative activity in HCT-116 cell lines with an IC50 of 0.0751 μM. Snail/HDAC-IN-1 showed good inhibitory effects on NCI-H522 (GI50 = 0.0488 μM), MDA-MB-435 (GI50 = 0.0361 μM), and MCF7 (GI50 = 0.0518 μM)[1].
Chemical Properties
Molecular Weight488.54
FormulaC24H21FN8OS
Cas No.2415281-52-4
Storage & Solubility Information
Storagekeep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 100 mg/mL (20.47 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.0469 mL10.2346 mL20.4692 mL102.3458 mL
5 mM0.4094 mL2.0469 mL4.0938 mL20.4692 mL
10 mM0.2047 mL1.0235 mL2.0469 mL10.2346 mL
20 mM0.1023 mL0.5117 mL1.0235 mL5.1173 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
1 Enter information below:
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