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Taraxerol
🥰Excellent
Catalog No. TN1077Cas No. 127-22-0
Alias Skimmiol, Alnulin
Taraxerol(Alnulin) is an anti-inflammatory and anticancer compound derived from dandelion.Taraxerol reduces acute inflammation and induces apoptosis by inhibiting the NF-κB signaling pathway.
Taraxerol
🥰Excellent
Purity: 98.92%
Catalog No. TN1077Alias Skimmiol, AlnulinCas No. 127-22-0
Taraxerol(Alnulin) is an anti-inflammatory and anticancer compound derived from dandelion.Taraxerol reduces acute inflammation and induces apoptosis by inhibiting the NF-κB signaling pathway.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $64 | In Stock | |
| 5 mg | $166 | In Stock | |
| 10 mg | $266 | In Stock | |
| 50 mg | Inquiry | In Stock |
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CitedSelect Batch
Purity:98.92%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Taraxerol(Alnulin) is an anti-inflammatory and anticancer compound derived from dandelion.Taraxerol reduces acute inflammation and induces apoptosis by inhibiting the NF-κB signaling pathway. |
| In vitro | Taraxerol (0-100 μM; 24 or 48 hours) significantly reduced cell viability to 95% (20 μM), 89.8% (40 μM), 82.6% (60 μM), 72.9% (80 μM), and 63.6% (100 μM). The cell viability of this compound in HeLa cells at 20 μM and 100 μM concentrations within 48 hours was 90.7% and 53.6%, respectively.[1] Taraxerol (80 μM; 24 or 48 hours) induces apoptosis and cell death in HeLa cells in a dose-dependent manner. Annexin V/PI double staining method showed that compared to the control group’s apoptotic cell count of 6.5% (early stage) and 0.5% (late stage), Taraxerol significantly induced apoptosis to 24.2% (early stage) and 16.2% (late stage).[1] |
| In vivo | Taraxerol (5 and 10 mg/kg; i.p.) reduces carrageenan-induced paw edema. The effect of 5mg/kg Taraxerol was significant (p<0.05) only after 4 hours of carrageenan treatment.[2] |
| Alias | Skimmiol, Alnulin |
| Molecular Weight | 426.72 |
| Formula | C30H50O |
| Cas No. | 127-22-0 |
| Smiles | CC1(C)CC[C@]2(C)CC=C3[C@]4(C)CC[C@H]5C(C)(C)[C@@H](O)CC[C@]5(C)[C@H]4CC[C@@]3(C)[C@@H]2C1 |
| Relative Density. | 1.01g/cm3 |
Storage & Solubility Information
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
| Solubility Information | DMSO: <1 mg/mL (Insoluble or slightly soluble)  THF: 5 mg/mL (11.72 mM), Sonication is recommended. Methanol: <1 mg/mL (Insoluble or slightly soluble) Ethanol: <1 mg/mL (Insoluble or slightly soluble) H2O: <0.1 mg/ml | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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