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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $64 | In Stock | |
5 mg | $166 | In Stock | |
10 mg | $266 | In Stock | |
50 mg | Inquiry | In Stock |
Description | Taraxerol(Alnulin) is an anti-inflammatory and anticancer compound derived from dandelion.Taraxerol reduces acute inflammation and induces apoptosis by inhibiting the NF-κB signaling pathway. |
In vitro | Taraxerol (0-100 μM; 24 or 48 hours) significantly reduced cell viability to 95% (20 μM), 89.8% (40 μM), 82.6% (60 μM), 72.9% (80 μM), and 63.6% (100 μM). The cell viability of this compound in Hela cells at 20 μM and 100 μM concentrations within 48 hours was 90.7% and 53.6%, respectively.[1] Taraxerol (80 μM; 24 or 48 hours) induces apoptosis and cell death in HeLa cells in a dose-dependent manner. Annexin V/PI double staining method showed that compared with the number of apoptotic cells in the control group at the early (6.5%) and late (0.5%) stages, Taraxerol could significantly induce cell apoptosis (24.2% in the early stage and 16.2% in the late stage).[1] |
In vivo | Taraxerol (5 and 10 mg/kg; i.p.) reduces carrageenan-induced paw edema. The effect of 5mg/kg Taraxerol was significant (p<0.05) only after 4 hours of carrageenan treatment.[2] |
Alias | Skimmiol, Alnulin |
Molecular Weight | 426.72 |
Formula | C30H50O |
Cas No. | 127-22-0 |
Storage | store at low temperature,keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||
Solubility Information | DMSO: <0.1 mg/ml THF: 5 mg/mL (11.72 mM) H2O: <0.1 mg/ml | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
THF
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